Effective Inhibition of MYC-Amplified Group 3 Medulloblastoma Through Targeting EIF4A1.

Yang ZhaoTiantian LiShuaiwei TianWei MengYi SuiJian YangBaocheng WangZhuangzhuang LiangHeng ZhaoYipeng HanYujie Tang Lei Zhang Jie Ma

Published in: Cancer management and research (2020)

Our investigation shows that interrupting MYC translation by EIF4A1 inhibition could be a potential effective therapeutic approach when treating patients with MYC-amplified G3-MB.

Keyphrases

transcription factor
cancer therapy
risk assessment
drug delivery
human health
climate change