KFP-1, a Novel Calcium-Binding Peptide Isolated from Kefir, Promotes Calcium Influx Through TRPV6 Channels.

Gary Ro-Lin ChangMin-Yu TuYu-Hsuan ChenKu-Yi ChangChien-Fu ChenJen-Chieh LaiYu-Tang TungHsiao-Ling ChenHueng-Chuen FanChuan-Mu Chen

Published in: Molecular nutrition & food research (2021)

These data suggest that KFP-1, a novel calcium-binding peptide, binds extracellular calcium ions and enters Caco-2 and IEC-6 cells, and promotes calcium uptake through TRPV6 calcium channels. The present study is of great importance for developing kefir-derived metal ion-binding peptides as functional nutraceutical additives.

Keyphrases

induced apoptosis
neuropathic pain
spinal cord injury
cell proliferation
binding protein
electronic health record
spinal cord
cell cycle arrest
deep learning
pi k akt