Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial.
Hiroto Matsui MatsuiShoichi HazamaMasao NakajimaMing XuSatoshi MatsukumaYukio TokumitsuYoshitaro ShindoShinobu TomochikaShin YoshidaMichihisa IidaNobuaki SuzukiShigeru TakedaShigefumi YoshinoTomio UenoMasaaki OkaHiroaki NaganoPublished in: Cancer immunology, immunotherapy : CII (2020)
The HSP70 mRNA-transfected DC therapy was performed safely as an adjuvant therapy. The prognosis of HSP70-expressing HCC cases could be expected to improve with this therapy.