Breed-specific reference sequence optimized mapping accuracy of NGS analyses for pigs.

Dan WangLiu YangChao NingJian-Feng LiuQiuyan Li

Published in: BMC genomics (2021)

This study showed that different reference sequences representing different genetic relationships to sample reads influenced mitogenome alignment, with the breed-specific reference sequences being optimal for mitogenome analyses, which provides a refined processing perspective for NGS data.

Keyphrases

high resolution
electronic health record
gene expression
copy number
genetic diversity
deep learning
data analysis