Targeting TNFRSF25 by agonistic antibodies and multimeric TL1A proteins co-stimulated CD8 + T cells and inhibited tumor growth.

Xueyuan LyuLinlin ZhaoSijia ChenYulu LiYajing YangHuisi LiuFang YangWenhui LiJianhua Sui

Published in: Journal for immunotherapy of cancer (2024)

Our data demonstrates the potential of activating TNFRSF25 by Abs and multimeric TL1A proteins for cancer immunotherapy and provides insights into their development astherapeutics.

Keyphrases

signaling pathway
electronic health record
cancer therapy
machine learning
drug delivery