Intratumoral T-cell and B-cell receptor architecture associates with distinct immune tumor microenvironment features and clinical outcomes of anti-PD-1/L1 immunotherapy.
Aimilia SchinaZsofia SztupinszkiInge Marie SvaneZoltan SzallasiGöran JönssonMarco DoniaPublished in: Journal for immunotherapy of cancer (2023)
Overall, these data indicate a currently unexplored immunological role of intratumoral B-cells associated with BCR diversity and antibody responses but independent of classical anticancer T-cells intratumoral activities.