Impact of Cryopreservation and Freeze-Thawing on Therapeutic Properties of Mesenchymal Stromal/Stem Cells and Other Common Cellular Therapeutics.
Chasen CottleAmanda Paige PorterAriel LipatCaitlin Turner-LylesJimmy NguyenGuido MollRaghavan ChinnaduraiPublished in: Current stem cell reports (2022)
Targeted research into optimizing the cryopreservation and freeze-thawing routines and the adjunct manufacturing process design may provide crucial advantages to increase both the safety and efficacy of cellular therapeutics in clinical use and to enable effective market deployment strategies to become economically viable and sustainable medicines.