Metabolic syndrome is associated with reduced flow mediated dilation independent of obesity status.
Victoria S SprungKelly A Bowden DaviesJuliette A NormanAndrew ThompsonKatie L MitchellJohn P H WildingGraham J KempDaniel J CuthbertsonPublished in: European journal of endocrinology (2020)
In this study cohort, components of MetS, rather than obesity per se, contribute to reduced FMD, which suggests a reduced bioavailability of nitric oxide and thus increased risk of CVD.