Mechanisms underlying the prolonged activation of the genioglossus following arousal from sleep.
Andrew DawsonJoanne AvraamChristian L NicholasAmanda KayTherese ThorntonNicole FeastMonika D FridgantFergal J O'DonoghueJohn TrinderAmy S JordanPublished in: Sleep (2023)
The sustained increase in genioglossal activity that occurs on return to sleep after arousal is primarily a result of persistent activity of inspiratory-modulated MUs, with a slight contribution from tonic units. Harnessing genioglossal activation following arousal may potentially be useful for preventing obstructive respiratory events.