Insulin attenuates LPS-induced cognitive impairment and ferroptosis through regulation of glucose metabolism in hippocampus.
Miao SunMin LiuQingxiao LiSiyuan LiuHuikai YangYuxiang SongMengyao QuXiaoying ZhangYulong MaWei-Dong MiPublished in: CNS neuroscience & therapeutics (2024)
Our findings underscore the therapeutic potential of insulin in alleviating LPS-induced cognitive impairment and ferroptosis by modulating glucose metabolism. This study offers a promising avenue for future interventions targeting cognitive decline.