Down-Regulation of CXCR4 in Mesenchymal Stem Cells by Septic Serum.
Mohammad Amin GhanbariTaghi Lashkar BoloukiPirasteh NorouziFatemeh Sadat BitarafHaniye BakhshiAmir AtashiPublished in: Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion (2022)
In our study, MSCs treated with septic serum were no longer able to migrate . Probably many variables such as source, dose, injection time, and injection route of MSCs after sepsis induction in the animal models are key factors for successful cell therapy.