Spontaneous remyelination in lesions protects the integrity of surrounding tissues over time in multiple sclerosis.

Vito A G RiciglianoMatteo ToniettoMariem HamzaouiÉmilie PoirionAndrea LazzarottoMichel BottlaenderPhilippe GervaisElisabeth MaillartBruno StankoffBenedetta Bodini

Published in: European journal of neurology (2022)

Intralesional remyelination is associated with the microstructural preservation of surrounding tissues, possibly preventing neuroaxonal damage resulting from Wallerian degeneration.

Keyphrases

multiple sclerosis
white matter
gene expression
oxidative stress