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Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy.

Jiabao ZhuangHanxiao YangYue LiBing WangNan LiNa Zhao
Published in: Chemical communications (Cambridge, England) (2020)
Two efficient photosensitizers (PSs) with aggregation-induced emission characteristics were designed and synthesized for specific lysosome-targeted photodynamic therapy (PDT). Both PSs efficiently discriminated Gram-positive bacteria from Gram-negative bacteria and killed Gram-positive bacteria through the PDT effect.
Keyphrases
  • photodynamic therapy
  • gram negative
  • fluorescence imaging
  • multidrug resistant
  • cancer therapy
  • fluorescent probe
  • living cells
  • drug delivery