IL-37 overexpression promotes endometrial regenerative cell-mediated inhibition of cardiac allograft rejection.

Hong QinChenglu SunYanglin ZhuYafei QinShaohua RenZhaobo WangChuan LiXiang LiBaoren ZhangJingpeng HaoGuangming LiHongda WangBo ShaoJingyi ZhangHao Wang

Published in: Stem cell research & therapy (2022)

IL-37 overexpression can promote the therapeutic effects of ERCs to inhibit acute allograft rejection and further prolong graft survival. This study suggests that gene-modified ERCs overexpressing IL-37 may pave the way for novel therapeutic options in the field of transplantation.

Keyphrases

cell therapy
cell proliferation
stem cells
liver failure
transcription factor
single cell
left ventricular
kidney transplantation
copy number
endometrial cancer
respiratory failure
hepatitis b virus