Association between polymorphisms on chromosome 17q12-q21 and rhinovirus-induced interferon responses.

Eteri RegisSara FontanellaJohn A CurtinAngela Pinot de MoiraMichael R EdwardsClare S MurrayAngela SimpsonSebastian L JohnstonAdnan Custovic

Published in: The Journal of allergy and clinical immunology (2024)

Polymorphisms on chromosome 17q12-q21 are associated with rhinovirus-induced IFN-β, suggesting a novel mechanism-impaired IFN-β induction-links 17q12-q21 risk alleles with asthma/wheeze.

Keyphrases

dendritic cells
high glucose
diabetic rats
immune response
chronic obstructive pulmonary disease
copy number
drug induced
endothelial cells
allergic rhinitis
respiratory tract