Immunological and inflammatory effects of infectious diseases in circadian rhythm disruption and future therapeutic directions.

Helen Huang Aashna Mehta Jacob B Kalmanovich Ayush Anand Maria Chilo Bejarano Tulika Garg Nida Khan Gauvain Kankeu Tonpouwo Anastasiia D Shkodina Mainak Bardhan

Published in: Molecular biology reports (2023)

It is shown that bidirectional relationships exist between circadian rhythm disruption and infectious process, which contains interplay between the host's and pathogens' circadian oscillator, immune response, and the influence of specific infectious. Further studies exploring the modulations of circadian rhythm and immunity can offer novel explanations of different susceptibilities to infection and can lead to therapeutic avenues in circadian immune modulation of infectious diseases.

Keyphrases

infectious diseases
immune response
atrial fibrillation
heart rate
oxidative stress
current status
multidrug resistant