Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect.
Renata Gonçalves DiasSandra Coccuzzo SampaioMorena Brazil Sant'AnnaFernando Queiroz CunhaJosé María GutiérrezBruno LomonteYara CuryGisele PicoloPublished in: The journal of venomous animals and toxins including tropical diseases (2017)
These results demonstrated the multi-mediated characteristic of the articular inflammation induced by MT-II, which demonstrates its relevance as a model for arthritis mechanisms and treatment evaluation.
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