Antimalarial evaluation of alkyl-linked bis-thiadiazine derivatives in murine model infected with two Plasmodium strains.
Katherine Loachamin-GualotuñaLilian M SpencerHortensia RodriguezAbigail Montero-CalderonBeatriz PerniaJulieta CoroMargarita SuarezFrancisco Javier Tingo-JácomeZully J Rodriguez-ParraJosé Manuel LozanoJesús A Cortés-VecinoPublished in: ADMET & DMPK (2023)
allowed us to conclude that some of them have an antimalarial effect; however, none of the tested compounds exceeded the efficiency of chloroquine.