Immune landscape and subtypes in primary resectable oral squamous cell carcinoma: prognostic significance and predictive of therapeutic response.
Pengfei DiaoYue JiangYuanyuan LiXiang WuJin LiChen ZhouLei JiangWei ZhangEnshi YanPing ZhangXu DingHeming WuHua YuanJinhai YeXiaomeng SongLinzhong WanYunong WuHongbing JiangYanling WangJie ChengPublished in: Journal for immunotherapy of cancer (2022)
Our results delineated immune landscape and subtypes in OSCC, consolidated their clinical values as robust biomarkers to predict patient survival and therapeutic benefits and reinforced key roles of TIIs and tumor-immune interactions underlying oral tumorigenesis, ultimately facilitating development of tailed immunotherapeutic strategies.