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Diversity, evolution, and classification of virophages uncovered through global metagenomics.

A David Páez-EspinoJinglie ZhouSimon RouxStephen NayfachGeorgios A PavlopoulosFrederik SchulzKatherine D McMahonDavid WalshTanja WoykeNatalia N IvanovaEmiley A Eloe-FadroshSusannah G TringeNikos C Kyrpides
Published in: Microbiome (2019)
Overall, our approach has increased the number of known virophage genomes by 10-fold and revealed patterns of genome evolution and global virophage distribution. We anticipate that the expanded diversity presented here will provide the backbone for further virophage studies.
Keyphrases
  • machine learning
  • deep learning
  • single cell
  • genome wide
  • case control
  • gene expression