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Multi-Omic blood analysis reveals differences in innate inflammatory sensitivity between species.

David J GregoryFeifei HanPeng LiMarina GritsenkoJennifer KyleFrank E RileyDeborah ChavezVania YotovaRenata H M SindeauxMohamed B F HawashFengyun XuLi-Yuan HungDouglas L HaydenRon G TompkinsRobert E LanfordLester KobzikJudith HellmanJonathan M JacobsLuis B BarreiroWenzhong XiaoH Shaw Warren
Published in: medRxiv : the preprint server for health sciences (2023)
Fundamental differences are present in blood of humans, mice and other species that differ in sensitivity to inflammation.
Keyphrases
  • oxidative stress
  • immune response
  • high fat diet induced
  • genetic diversity
  • type diabetes
  • adipose tissue