Possible Prophylactic Effects of Sulforaphane on LPS-Induced Recognition Memory Impairment Mediated by Regulating Oxidative Stress and Neuroinflammatory Proteins in the Prefrontal Cortex Region of the Brain.
Noor Ahmed AlzahraniKhulud Abdullah BahaidrahRasha A MansouriRahaf Saeed AldhahriGamal S Abd El-AzizBadrah S AlghamdiPublished in: Biomedicines (2024)
The obtained results suggested that SFN has a potential protective property to mitigate the behavioral and biochemical impairments induced by chronic LPS administration and suggested to be via an AMPK/caspase-3-dependent manner.
Keyphrases
- lps induced
- prefrontal cortex
- inflammatory response
- oxidative stress
- induced apoptosis
- cell death
- resting state
- white matter
- working memory
- skeletal muscle
- dna damage
- diabetic rats
- ischemia reperfusion injury
- functional connectivity
- cerebral ischemia
- human health
- protein kinase
- anti inflammatory
- endoplasmic reticulum stress
- signaling pathway
- multiple sclerosis
- subarachnoid hemorrhage
- heat shock
- heat shock protein