FOXO3 regulates a common genomic program in aging and glioblastoma stem cells.
Amanda J AudesseGalina KarashchukZachary A GardellNelli S LakisSun Y Maybury-LewisAbigail K BrownDena S LeemanYee Voan TeoNicola NerettiDouglas C AnthonyAlexander S BrodskyAshley E WebbPublished in: Aging and cancer (2021)
This work identifies a FOXO-associated transcriptional program that correlates between GSCs and aging NSCs and is enriched for metabolic and stemness pathways connected with GBM and aging.