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[Drug therapy's new options in the treatment of the severe irritable bowel syndrome].

A A ViaznikovaI N RuchkinaG M DiukovaN V RomashkinaL K IndejkinaD A DegterevA I Parfenov
Published in: Terapevticheskii arkhiv (2023)
The severe course of IBS-D is mainly associated with the patients' individual characteristics and anxiety or anxiety-depressive syndromes. The positive impact of duloxetine therapy in severe IBS-D with extraintestinal manifestations is associated with the regulation of serotonergic and noradrenergic activity of the central.
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