Differences in the Neanderthal BRCA2 gene might be related to their distinctive cognitive profile.
Antonio Benítez-BurracoPublished in: Hereditas (2018)
The unique divergence of the BRCA2 gene in Neanderthals compared to modern humans has been hypothesized to account for a differential susceptibility to cancer. However, the role of the gene in brain development and its connection with autism suggest that these differences might be (also) related to the more encapsulated nature of the Neanderthal cognition and their (inferred) autistic-like features.
Keyphrases
- copy number
- genome wide
- genome wide identification
- white matter
- autism spectrum disorder
- papillary thyroid
- dna methylation
- mild cognitive impairment
- intellectual disability
- gene expression
- young adults
- multiple sclerosis
- genome wide analysis
- resting state
- brain injury
- subarachnoid hemorrhage
- drug induced
- breast cancer risk
- lymph node metastasis