Prevalence of fibroblast growth factor receptor 1 (FGFR1) amplification in squamous cell carcinomas of the head and neck.

Till Sebastian ClauditzArne BöttcherHenning HankenKerstin BorgmannGuido SauterWaldemar WilczakTobias GrobAdrian Münscher

Published in: Journal of cancer research and clinical oncology (2017)

Head and neck cancers are recurrently affected by FGFR1 amplification, with a predominance in cancers of the oral cavity. Finding only one HPV positive and FGFR1 amplified cancer argues against a causal relationship between HPV and FGFR1 amplifications.

Keyphrases

squamous cell
high grade
nucleic acid
papillary thyroid
risk factors
childhood cancer