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Neurodegenerative disorders: Assessing the impact of natural vs drug-induced treatment options.

Sakshi MathurChaitali GawasIffat Zareen AhmadMinal WaniHeena Tabassum
Published in: Aging medicine (Milton (N.S.W)) (2023)
Neurodegenerative illnesses refer to the gradual, cumulative loss of neural activity. Neurological conditions are considered to be the second leading cause of mortality in the modern world and the two most prevalent ones are Parkinson's disease and Alzheimer's disease. The negative side effects of pharmaceutical use are a major global concern, despite the availability of many different treatments for therapy. We concentrated on different types of neurological problems and their influence on targets, in vitro, in vivo, and in silico methods toward neurological disorders, as well as the molecular approaches influencing the same, in the first half of the review. The bulk of the second half of the review focuses on the many categories of treatment possibilities, including natural and artificial. Nevertheless, herbal treatment solutions are piquing scholarly attention due to their anti-oxidative properties and accessibility. However, more quality investigations and innovations are undoubtedly needed to back up these conclusions.
Keyphrases
  • drug induced
  • liver injury
  • type diabetes
  • cognitive decline
  • risk factors
  • coronary artery disease
  • cerebral ischemia
  • molecular docking
  • quality improvement
  • blood brain barrier
  • bone marrow
  • cell therapy