Differential regulation of autophagy by STAU1 in alveolar rhabdomyosarcoma and non-transformed skeletal muscle cells.

Bernard J JasminTara E Crawford ParksAymeric Ravel-ChapuisAlex MacKenzieJocelyn CôtéKyle N CowanBernard J Jasmin

Published in: Cellular oncology (Dordrecht) (2021)

Together, our data indicate an effect of STAU1 on autophagy regulation in ARMS cells and its differential role in non-transformed skeletal muscle cells. Our findings suggest a cancer-specific potential of targeting STAU1 for the treatment of ARMS.

Keyphrases

metabolic syndrome
induced apoptosis
skeletal muscle
cell cycle arrest
endoplasmic reticulum stress
cell death
signaling pathway
oxidative stress
squamous cell carcinoma
risk assessment
machine learning
papillary thyroid
climate change
deep learning