Oxidative stress biomarkers and their relationship with cytokine concentrations in overweight/obese pregnant women and their neonates.
María Hernández-TrejoAraceli Montoya-EstradaYessica Torres-RamosAurora Espejel-NúñezAlberto Guzmán-GrenfellRosa Morales-HernándezMaricruz Tolentino-DoloresEstibalitz Laresgoiti-ServitjePublished in: BMC immunology (2017)
Oxidative stress biomarkers differ between mothers and offspring and can predict maternal and newborn cytokine concentrations, indicating a potential role for oxidative stress in foetal metabolic and immunologic programming. Moreover, maternal obesity and diabetes may affect maternal microenvironments, and oxidative stress related to these can have an impact on the placenta and foetal growth.
Keyphrases
- oxidative stress
- pregnant women
- weight loss
- type diabetes
- dna damage
- pregnancy outcomes
- birth weight
- ischemia reperfusion injury
- diabetic rats
- weight gain
- metabolic syndrome
- induced apoptosis
- physical activity
- bariatric surgery
- preterm infants
- endoplasmic reticulum stress
- low birth weight
- heat shock protein
- heat stress