LDL lowering effect of PCSK9 inhibition is reduced in women.

V A MyasoedovaA RimbertM CameraC Le MayRomain CapouladeB CariouPoggio Paolo

Published in: European heart journal. Cardiovascular pharmacotherapy (2023)

These results demonstrate by complementary approaches that the decrease in LDL-C mediated by PCSK9 inhibition is slightly, but significantly, less marked in women than in men. These data reinforce the need for specific studies to develop sex-specific recommendations for the management of ASCVD in women.

Keyphrases

polycystic ovary syndrome
pregnancy outcomes
low density lipoprotein
cervical cancer screening
breast cancer risk
type diabetes
electronic health record
insulin resistance
pregnant women
machine learning
middle aged
artificial intelligence
case control