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Does Reinke's Edema Grade Determine Premalignant Potential?

Raluca GrayHoward HermanJuan LinMelin Tan
Published in: The Annals of otology, rhinology, and laryngology (2018)
Size of RE lesion does not reflect premalignancy. The majority of RE lesions, regardless of size, have little to no premalignant potential. Severe dysplasia/carcinoma in situ may be more likely seen in grade 4 lesions; however, the paucity of severe dysplasia published in RE data and in this cohort preclude any formal inference. Further study of grade 4 lesions is warranted.
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