Genetic variation supports a causal role for valproate in prevention of ischemic stroke.

Ernst Mayerhofer Livia Parodi Kaavya NarasimhaluStefan WolkingAndreas HarloffMarios K GeorgakisJonathan RosandChristopher D Anderson

Published in: International journal of stroke : official journal of the International Stroke Society (2023)

UK Biobank participant data are available after approval of a research proposal. The weights of the used genetic scores are available in the Supplemental Tables.

Keyphrases

electronic health record
atrial fibrillation
genome wide
big data
copy number
gene expression
dna methylation
drug administration