Viral metagenomic sequencing in the diagnosis of meningoencephalitis: a review of technical advances and diagnostic yield.
Ellen C CarboIvar BlankenspoorJelle J GoemanAloys C M KroesEric C J ClaasJutte J C De VriesPublished in: Expert review of molecular diagnostics (2021)
The last decade has shown major advances in technical possibilities for using mNGS in diagnostic settings including cloud-based analysis. An additional advance may be the current established infrastructure of platforms for bioinformatic analysis of SARS-CoV-2, which may assist to pave the way for global use of clinical metagenomics.