Profiling plasma alterations of extracellular vesicles in patients with acutely decompensated cirrhosis and bacterial infection.
Elena CampelloAlberto ZanettoClaudia M RaduSerena ToffaninSarah ShalabySabrina GavassoStefania RizzoNicola PerinPaolo AngeliPatrizia BurraMarco SenzoloPaolo SimioniPublished in: Liver international : official journal of the International Association for the Study of the Liver (2024)
Bacterial infections are associated with particular alterations of plasma EVs profile in decompensated cirrhosis. Bacterial infections trigger the release of EVs originating from various cell types, which may tip the precarious hemostatic balance of patients with acutely decompensated cirrhosis towards hyper- or hypocoagulability.