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Potential utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction-associated steatohepatitis.

Junyan LyuHikari OkadaHajime SunagozakaKazunori KawaguchiTetsuro ShimakamiKouki NioKazuhisa MuraiTakayoshi ShirasakiMika YoshidaKuniaki AraiTatsuya YamashitaTakuji TanakaKenichi HaradaToshinari TakamuraShuichi KanekoTaro YamashitaMasao Honda
Published in: Hepatology communications (2024)
Short-term l-carnitine administration ameliorated MASH through its anti-inflammatory effects. Long-term l-carnitine administration potentially improved the steatosis and fibrosis of MASH and may eventually reduce the risk of HCC.
Keyphrases
  • insulin resistance
  • oxidative stress
  • liver fibrosis
  • adipose tissue
  • climate change