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The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity.

Ross A CardarelliKaren JonesLucie I PisellaHeike J WobstLisa J McWilliamsPaul Thomas SharpeMatthew P BurnhamDavid J BakerIlona ChudotvorovaJustine GuyotLiliya SilayevaDanielle H MorrowNiek DekkerStephen ZichaPaul A DaviesJörg HolenzMark E DugganJohn DunlopRobert J MatherQi WangIgor MedinaNicholas J BrandonTarek Z DeebStephen J Moss
Published in: Nature medicine (2019)
Keyphrases
  • small molecule