Login / Signup

Metabolic switching, growth kinetics and cell yields in the scalable manufacture of stem cell-derived insulin-producing cells.

Diepiriye G IworimaRobert K BakerCara EllisChris SherwoodLisa ZhanAlireza RezaniaJames M PiretTimothy J Kieffer
Published in: Stem cell research & therapy (2024)
This study demonstrates process parameters such as glucose consumption and lactate production rates that may be used to facilitate the scalable manufacture of stem cell-derived insulin-producing cells.
Keyphrases
  • induced apoptosis
  • type diabetes
  • cell cycle arrest
  • endoplasmic reticulum stress
  • single cell
  • glycemic control
  • oxidative stress
  • cell death
  • stem cells
  • cell therapy
  • blood pressure
  • adipose tissue