Intestinal epithelia and myeloid immune cells shape colitis severity and colorectal carcinogenesis via High-mobility group box protein 1.

Katharina FoelschPenelope PelczarElisabeth ZierzStephanie KondratowiczMinyue QiChristian MüllerMalik AlawiSina HuebenerTill ClauditzNicola GaglianiSamuel HuberPeter Huebener

Published in: Journal of Crohn's & colitis (2024)

Enterocytes and myeloid cells context-dependently regulate host responses to severe colitis and maladaptive intestinal wound healing via HMGB1.

Keyphrases

wound healing
induced apoptosis
dendritic cells
bone marrow
acute myeloid leukemia
binding protein
cell cycle arrest
ulcerative colitis
transcription factor
protein protein
oxidative stress
drug induced