Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: a comparison of patients with and without COVID-19.
Sachin J ShahPeter N BarishPriya A PrasadAmy L KistlerNorma F NeffJack KammLucy M LiCharles Y ChiuJennifer M BabickMargaret C FangYumiko Abe-JonesNarges AlipanahFrancisco N AlvarezOlga B BotvinnikJennifer M DavisGloria D CastenadaCLIAHub ConsortiumRand M DadasovichXianding DengJoseph L DerisiAngela M DetweilerScot FedermanJohn R HaliburtonSamantha L HaoAndrew D KerkhoffRenuka KumarKatherine MalcolmSabrina A MannSandra P MartinezRupa MaryaEran MickLusajo L MwakibeteNader NajafiMichael J PelusoMaira S PhelpsAngela O PiscoKalani RatnasiriLuis A RubioAnna B SellasKyla D SherwoodJonathan SheuNatasha SpottiswoodeMichelle TanGuixa YuKirsten N KangelarisCharles R LangelierPublished in: medRxiv : the preprint server for health sciences (2020)
While we found differences in clinical features of COVID-19 compared to other acute respiratory illnesses, there was significant overlap in presentation and comorbidities. Patients with COVID-19 were more likely to be admitted to the hospital, have longer hospitalizations and develop ARDS, and were unlikely to have co-existent viral infections. These findings enhance understanding of the clinical characteristics of COVID-19 in comparison to other acute respiratory illnesses. .