Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.

Wenjun Zeng Yinan Ji Haiping Zhang Liusheng Chen Li Du Ruiwei Guo

Published in: Genetics research (2021)

These data suggest that concurrent inhibition of TRPC4 and TRPC5 inhibits VSMCs proliferation without affecting VECs, thus providing novel targets for developing pharmacological agents for drug-eluting stents.

Keyphrases

cell proliferation
vascular smooth muscle cells
smooth muscle
cell cycle
signaling pathway
angiotensin ii
pi k akt
endothelial cells
electronic health record
emergency department
big data
radiation therapy
locally advanced
deep learning
rectal cancer