Methylation Status of GLP2R, LEP and IRS2 in Small for Gestational Age Children with and without Catch-up Growth
Mario Jr AnguloDiana Ramírez-MontañoLaura Alejandra Torres CanchalaXimena Garcia QuinteroRodrigo LemusAna M. AristizabalDanielle Floyd-AristizábalDiana M. DávalosLorena Díaz-OrdóñezHarry PachajoaPublished in: Journal of clinical research in pediatric endocrinology (2020)
There is no association between IRS2 methylation and catch-up growth among SGA patients. LEP and GLP2R were methylated in all SGA patients. Gene methylation may be implicated in metabolic disease later in life. More studies should be performed to confirm this hypothesis.