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Which comes first in type 1 diabetes: Autoimmunity or dysglycemia?

Hiroshi Ikegami
Published in: Journal of diabetes investigation (2023)
A recent study by Warncke et al. suggested that islet autoimmunity is associated with or preceded by insults or changes to the pancreatic islets that impair glucose homeostasis, raising the possibility that β-cell insult occurs first, followed by autoimmunity to islets.
Keyphrases
  • type diabetes
  • celiac disease
  • single cell
  • cell therapy
  • cardiovascular disease
  • glycemic control
  • insulin resistance
  • blood glucose
  • stem cells
  • adipose tissue
  • bone marrow