The Antiobesity Effect of GLP-1 Receptor Agonists Alone or in Combination with Metformin in Overweight /Obese Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.
Xiaorui LyuTaibiao LyuXue WangHuijuan ZhuHui PanLinjie WangHongbo YangFeng Ying GongPublished in: International journal of endocrinology (2021)
Our meta-analysis demonstrated that the antiobesity effect of GLP-1RAs alone or combined with MET was superior to MET alone in terms of weight loss, the reduction of waist circumference, and BMI. More large-scale, high-quality RCTs are needed to further confirm these results in PCOS patients.
Keyphrases
- weight loss
- body mass index
- systematic review
- polycystic ovary syndrome
- bariatric surgery
- end stage renal disease
- newly diagnosed
- weight gain
- roux en y gastric bypass
- ejection fraction
- tyrosine kinase
- gastric bypass
- peritoneal dialysis
- type diabetes
- prognostic factors
- physical activity
- body weight
- obese patients
- wild type
- glycemic control
- pregnancy outcomes