MAESTRO-Pool Enables Highly Parallel and Specific Mutation-Enrichment Sequencing for Minimal Residual Disease Detection in Cohort Studies.
Timothy BlewettJustin RhoadesRuolin LiuKan XiongSainetra SridharAndjela CrnjacJu ChengAleigha R LawlessDennie T FrederickKeith T FlahertyGerassimos Mike MakrigiorgosViktor A AdalsteinssonPublished in: Clinical chemistry (2023)
MAESTRO-Pool enables massively parallel, tumor-informed MRD testing with concurrent benchmarking of bespoke MRD tests. Meanwhile, our new MRD caller enables more mutations and cfDNA molecules to be tested without compromising specificity. These improve the ability for detecting traces of MRD from blood.
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