Infectious complications in pediatric allogeneic hematopoietic stem cell transplantation recipients-A retrospective clinical and epidemiological cohort study.
Tyane de Almeida PintoBruno Araújo JardimGiovanni Luís BredaHugo Manuel Paz MoralesCarmem BonfimSonia Maria RaboniPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2020)
The clinical profile of HSCT-related infections in this cohort suggests that prognosis in allogeneic HSCT is influenced by the source of stem cells (CB having worse prognosis), presence of acute GVHD and complications arising from fungal infections. The appropriate management of these factors has the potential to improve the overall prognosis rates in pediatric allogeneic HSCT recipients.
Keyphrases
- hematopoietic stem cell
- allogeneic hematopoietic stem cell transplantation
- stem cells
- stem cell transplantation
- acute myeloid leukemia
- bone marrow
- acute lymphoblastic leukemia
- risk factors
- liver failure
- kidney transplantation
- high dose
- low dose
- intensive care unit
- cell therapy
- young adults
- respiratory failure
- hepatitis b virus
- mesenchymal stem cells
- climate change
- childhood cancer