T1w/T2w ratio maps identify children with autism spectrum disorder and the relationships between myelin-related changes and symptoms.

Shujun ZhangLiping JiangZhe HuWenjing LiuHao YuYao ChuJiehuan WangYueqin Chen

Published in: Progress in neuro-psychopharmacology & biological psychiatry (2024)

Our findings suggest that microstructural abnormalities in myelination contribute to autistic symptoms and so are potentially promising therapeutic targets as well as biomarkers for ASD diagnosis.

Keyphrases

white matter
autism spectrum disorder
sleep quality
attention deficit hyperactivity disorder
intellectual disability
multiple sclerosis