Optogenetic Functional Activation Is Detrimental During Acute Ischemic Stroke in Mice.

Kazutaka Sugimoto David Y Chung Paul Fischer Tsubasa TakizawaTao QinMohammad A Yaseen Sava Sakadzic Cenk Ayata

Published in: Stroke (2024)

Our data suggest that increased neuronal activity during acute focal arterial occlusions can be detrimental, presumably due to increased metabolic demand, and may have implications for the clinical management of hyperacute stroke patients.

Keyphrases

acute ischemic stroke
liver failure
respiratory failure
drug induced
big data
type diabetes
aortic dissection
high fat diet induced
machine learning
cerebral ischemia
metabolic syndrome
blood brain barrier
acute respiratory distress syndrome
wild type