Sex-specific associations of insulin resistance with chronic kidney disease and kidney function: a bi-directional Mendelian randomisation study.

Published in: Diabetologia (2020)

Genetically predicted fasting insulin was sex-specifically associated with CKD and unhealthier kidney function but was not affected by kidney function. Graphical abstract.

Keyphrases

chronic kidney disease
insulin resistance
type diabetes
end stage renal disease
adipose tissue
high fat diet
metabolic syndrome
glycemic control
skeletal muscle
polycystic ovary syndrome
blood glucose
high fat diet induced