Impact of histaminergic H3 receptor antagonist on hypoglossal nucleus in chronic intermittent hypoxia conditions.

Liang XieQinhan WuWeiping HuXu WuGuiling XiangShengyu HaoHan GuoShan-Qun Li

Published in: Psychopharmacology (2020)

This investigation studied the impacts of ciproxifan on the HN and TMN in CIH conditions and revealed that the negative effects on the HN and TMN caused by CIH could be partly ameliorated by ciproxifan, which might open new perspectives for the development of pharmacological treatment for OSA.

Keyphrases

obstructive sleep apnea
minimally invasive
single cell
combination therapy
replacement therapy