Prognostic value of serum/plasma neurofilament light chain for COVID-19-associated mortality.

Ruturaj R MasvekarPeter KosaKimberly JinKerry DobbsMichael A StackRiccardo CastagnoliVirginia QuaresimaHelen C SuLuisa ImbertiLuigi D NotarangeloBibiana Bielekova

Published in: Annals of clinical and translational neurology (2022)

A substantial increase in serum/plasma NfL reproducibly enhanced COVID-19 mortality prediction. Combined with other prognostic markers, such as ALC and LDH that are routinely measured in ICU patients, NfL measurements might be useful to identify the patients at a high risk of COVID-19-associated mortality, who might still benefit from escalated care.

Keyphrases

coronavirus disease
sars cov
cardiovascular events
end stage renal disease
healthcare
risk factors
ejection fraction
newly diagnosed
chronic kidney disease
respiratory syndrome coronavirus
palliative care
prognostic factors
peritoneal dialysis
coronary artery disease
type diabetes